L-TheanineTea includes the special amino acid L-theanine, which regulates aspects of brain function in people. Tea antioxidants and catechins such as epigallocatechin gallate represent 42% of the dry weight of brewed green tea, while amino acid theanine accounts for only 3%. Research studies with human electroencephalography (EEG) have revealed that L-theanine has a direct effect on the brain. All at once with the boost in chemicals that promote a sense of calm, L-theanine decreases the level of chemicals in the brain that are connected with stress and anxiety. Research has actually revealed that L-theanine can improve sleep quality not just by serving as a sedative however likewise by lowering anxiety and promoting relaxation. Scientists discovered in one study that doses of 250 mg and 400 mg L-theanine respectively improved the sleep of animals and human beings (16 ). The researchers likewise discovered that the drug reduced stress and anxiety and improved symptoms. L-theanine and caffeine mixes can influence human cognition, as revealed by alpha-band oscillatory activity and attention task. L-theanine can be used together with caffeine to improve cognitive capabilities. The impact of 3 primary components of green tea against weight problems: catechin, caffeine and theanine in mice. Kakuda T. Neuroprotective result of green tea parts theanins and catechins. Impacts of L-theanine and caffeine in combination with caffeine on cognition and mood. Evaluation of the impacts of caffeine and theanine on preserving awareness and continual attention throughout tasks. A double-blind, placebo-controlled study to examine the result of the tea components L-theanine, caffeine, epigallocatechin gallatecaffeine and L-anine. L-theanine is an amino acid found in green and black tea and mushrooms. It is also used by some people to aid with low stress and anxiety and as a sleep aid. Since it is a substance that naturally occurs in green tea and black tea, it is likewise offered as a supplement. L-theanine in green tea produces a tasty taste understood as umami taste. Tea is the most common food source for L-theanine, but it can also be found in some types of fungi. In foods such as green tea, L-anine is believed to be a source of umami, a spicy, brittle taste. A study discovered that individuals who experienced hypertension during a certain psychological task discovered that L-theanine helped in reducing the increase in high blood pressure. In another research study, it assisted improve sleep and mood in cats, but did not have the very same result on disturbed consuming and drinking habits. esearch likewise suggests that L-theanine in green and black tea can contribute to a sense of relaxation by reducing the resting heart rate of an individual. In 2016 Scholey and his colleagues reported that subjects who consumed a nutrient drink that contained 200 milligrams of L-theanine (roughly the quantity found in eight cups of tea) had lower cortisol levels and reported feeling more relaxed during stress-inducing tasks than those who consumed a placebo4. A small research study showed that the combination of L-theanine and caffeine (40 mg) assisted a group of young people to concentrate on physically demanding tasks more effectively. Theanine acts as a neurotransmitter in the brain and can reduce blood pressure in hypertensive rats. Many research studies on theanine have actually been performed in mix with caffeine, which is found in tea. These research studies have actually shown that the combination has no impact on mood, and they have likewise found that it has little or no effect. Kinetics L-theanine uptake and metabolism in healthy individuals was equivalent to the consumption of green tea L-theanine capsules. The theanine material showed a correlation with related gene expression levels in the culture and tissues of tea plants in order to determine the integrated effect of metabolic genes. The correlation between metabolism of theanins and associated gene expression profiles and the content of theanins was examined in this study. Theanine acts as a neurotransmitter in the brain and can lower blood pressure in hypertensive rats. Numerous studies on theanine have been conducted in mix with caffeine, which is found in tea. These studies have shown that the mix has no impact on state of mind, and they have also discovered that it has little or no impact. Kinetics L-theanine uptake and metabolic process in healthy individuals was equivalent to the consumption of green tea L-theanine capsules. The theanine material showed a correlation with related gene expression levels in the culture and tissues of tea plants in order to determine the integrated result of metabolic genes. The connection in between metabolic process of theanins and related gene expression profiles and the content of theanins was examined in this study. A double-blind, placebo-controlled research study to examine the impact of the tea elements L-theanine, caffeine, epigallocatechin gallatecaffeine and L-anine. L-theanine is an amino acid discovered in black and green tea and mushrooms. Tea is the most typical food source for L-theanine, but it can likewise be discovered in some types of fungis. Kinetics L-theanine uptake and metabolism in healthy individuals was equivalent to the intake of green tea L-theanine pills. Kinetics L-theanine uptake and metabolism in healthy participants was equivalent to the consumption of green tea L-theanine capsules. For individuals with type 2 diabetes, a metabolic syndrome identified by insulin resistance and increased abdominal fat, the suggested daily consumption is 1,000 mg GTF (glucose tolerance element) in chromium form, which is utilized by the body. Chromium picolinate supplements lowers weight gain and increases insulin sensitivity in people with Type 2 diabetes. Studies reveal that chromium preparations can be helpful in individuals with type 2 diabetes, insulin resistance and prediabetes. Share on Pinterest Chromium increases insulin level of sensitivity, which assists the body process blood glucose. While some clinical trials have actually shown no benefit, other medical trials report that the supplements lower blood sugar level levels and insulin levels that individuals with diabetes requirement. People with type 2 diabetes taking chromium picolinate had better HbA1c levels, used to control long-lasting blood sugar levels, in a properly designed research study than those who consumed a placebo. A study carried out by the Human Nutrition Research Center of the United States Department of Agriculture found that individuals who were treated with type 2 diabetes and received either placebo or a chromium preparation over a four-month period continued to take normal medications and did not alter their consuming habits; the group who got extra chromium reduced insulin and cholesterol levels than the placebo group. Another of these research studies discovered that when people with type 2 diabetes for a month got chloride supplements two times a day, their insulin and cholesterol levels dropped. Previous research studies have actually shown that insulin resistance is the main element for clinical response to chromium25,37-39. In people with type 2 diabetes who utilized sulfonylurea, Martin39 revealed that chromium picolinate enhanced insulin sensitivity and glucose control and lowered body weight and visceral fat compared to placebo. While previous research study failed to validate that additional chromium helps individuals with minimal glucose tolerance due to type 2 diabetes, current studies have revealed that it can help treat diabetes by lowering blood fat levels, improving weight-loss and improving body composition. Chromium supplements did not increase weight, blood sugar, body fat portion or fat levels in a research study of 80 overweight and overweight adults and women with increased waist area. Current research suggests that research studies reporting a little reduction in body weight after supplementation with chromium have significant limitations. A research study found that females who took in nutrient and energy-based items and whose energy consumption was just controlled by chromium picolinate supplementation had no effect on weight, body mass or iron levels. In a brand-new study, scientists at the University of Miami evaluated data on the results of chromium supplements on blood sugar for 3 decades and concluded that chromium supplements in healthy people or diabetics are not effective in reducing fasting blood sugar level. The study, entitled "Improving metaanalytic methods to show the impact of a chromium supplement on fasting glucose - toxicity," was released in the journal Biological Trace Elements Research. The study was designed to assess the impacts of chromium picolinate supplementation in combination with a dietary education intervention for weight-loss in guys and ladies and to assess whether the impacts are because of anthropometry or body fat distribution. Chromium is a vital mineral that plays an useful function in controling insulin, the hormone that controls blood sugar and helps to carry glucose to cells where it can be used to produce energy in the body. Chromium plays a function in the insulin signaling pathways that permit our body to manage the quantity of sugar we soak up, which helps balance blood sugar levels and gives us stable energy. Yeast is a high source of chromium and has been shown to support sugar metabolism and glucose type in the blood which is advantageous in preventing glucose intolerance, insulin resistance and diabetes formation. There is scientific proof that blended chromium supplementation can have a positive effect on blood sugar control and weight loss, as well as on diabetes and other illness. In one study chromium group (600 mg per day) lost 84% of weight in fat and 16% in muscle, while placebo group lost 8% in fat and 92% muscle loss. In addition, in a Louisiana State University study, 42% of females who consumed 1,000 milligrams of chromium picolinate daily had actually decreased yearnings for carbohydrates and fat foods and a minor loss of body weight. Because weight problems is more uniformly distributed and is associated with insulin resistance, we think that chromium may support weight loss. Due to the considerable effects accomplished by higher dosages of chromium picolinate, Gunton et al. The FDA issued an unfavorable study of chromium for diabetes with 800 mg of chromium picolinate and 100 mg of elemental chromium (about 12% diet plan).21 Another scientist released an action criticising the study for insufficient dosages. 24 Gunton used to the FDA for qualified healthcare, however the only allowed claim concerned minimizing insulin resistance based upon a study utilizing 500 mg of elemental chromium and 4,000 mg of hormonal agent per day. Another research study consisted of in the meta-analysis and worth keeping in mind in seclusion was an eight-month randomised, double-blind placebo-controlled trial for 29 people with insulin resistance and prediabetes who received 1000 mg of chromia picolinated daily and given 100 mg of elemental chromium. Chromium picolinate has actually ended up being a popular dietary supplement for professional athletes and bodybuilders who use it to maintain muscle mass during exercise and promote weight loss. Chromium GTF-200, a nicotinic acid has actually been revealed to help metabolize fat, enhance glucose and insulin metabolic process, preserve healthy cholesterol and blood sugar levels, convert proteins into muscles and convert sugars into energy. Scientists have studied dietary supplements such as chromium picolinate to support weight-loss and changes in body composition, especially low iron levels in females who consume nutrient and energy-based items. Studies reveal that chromium preparations can be valuable in individuals with type 2 diabetes, insulin resistance and prediabetes. A study performed by the Human Nutrition Research Center of the US Department of Agriculture discovered that individuals who were treated with type 2 diabetes and got either placebo or a chromium preparation over a four-month period continued to take typical medications and did not change their consuming habits; the group who got additional chromium decreased insulin and cholesterol levels than the placebo group. In a new research study, scientists at the University of Miami analyzed information on the results of chromium supplements on blood sugar for three decades and concluded that chromium supplements in healthy individuals or diabetics are not effective in decreasing fasting blood sugar. The FDA released an unfavorable study of chromium for diabetes with 800 mg of chromium picolinate and 100 mg of elemental chromium (about 12% diet plan).21 Another researcher released an action criticising the research study for inadequate dosages. Another study included in the meta-analysis and worth keeping in mind in isolation was an eight-month randomised, double-blind placebo-controlled trial for 29 individuals with insulin resistance and prediabetes who got 1000 mg of chromia picolinated per day and given 100 mg of essential chromium.
L CarnitineDue to the fact that it transfers fatty acids from the blood to mitochondria where they can be utilized for energy production, l-carnitine is an important weapon for weight loss. Some individuals with diabetes of all kinds might benefit from an L-cannitin supplement because it can help to lower blood glucose levels. L-carnitine not just assists the body burn fuel as effectively as possible to increase energy, however also improves athletic performance and endurance by preventing the buildup of lactic acid, which is among the primary reasons for exhaustion during physical activity. Research studies have actually shown that patients who use L-carcitine for weight loss experience a decrease in body fat, an increase in muscle mass, improvements in strength and stamina and a decrease in fatigue. It is thought to help reduce and strengthen muscles fat in the body, assisting individuals to feel less tired and improve weight-loss. It is very important to note that L-carnitine will not assist you burn fat and drop weight if you do not combine it with a healthy diet plan and exercise regimen. If you are vegan or on a restricted diet plan, the injection straight into your body supplies you with the healthy carnitine your body needs to charge energy and burn fat. At MD Ageless Solutions, we discovered the most effective method to attend to weight-loss issue with the help of L-carbonitin preparations that are understood to assist weight reduction and offer other health advantages. If you do not consume meat or dairy products or have a limited diet plan, an injection of L-carnitine can provide all the healthy carnitine your body needs to recharge energy and burn fat. On the other hand, L-carbonitin supplements are natural items that stimulate the production of L-carnitines with the sole function of promoting effective weight loss and weight-loss. They can be utilized for those who are deficient in L-carnitine, wish to drop weight and construct a body at a faster speed, or consume L-carnitine-rich diet plans that work well. L-carnitine is an amino acid kept in the skeletal muscles, heart and brain of the body and produced by the liver and kidneys to transform body fat into energy. This is among the main reasons lots of weight reduction supplements incorporate it due to its native function in the body. Carnitine, as a sort of amino acid, take advantage of the energy material by transferring fats to mitochondria where they can be burned and utilized as fuel. For this reason, lots of people take carnitine as a weight-loss supplement to promote fat burning. For many individuals, L-carnitine is a method to speed up weight reduction and weight loss. Advantages of carnitine consist of improving brain function, avoiding muscle damage, managing blood sugar level and increasing endurance. Bear in mind that while carnitine can improve weight loss and weight reduction in some people, it ought to be used with a healthy diet plan and active way of life to get the most outcomes. Weight loss Since L-carnitine helps to burn fat for energy, numerous individuals presume that more of it will help them slim down. It has actually been suggested however that its capability to transfer more fat acids into the cells to burn energy makes it a reliable efficiency booster and it is useful for weight loss and weight loss. Given that it is used by athletes all over the world for fat loss, it can improve the way your body uses fat as fuel, leading to better exercise performance3. It is a popular supplement for both weight-loss and weight loss and must be taken as an excellent addition to your workout program. The mix of adenosine and L-carnitine can assist you boost your weight loss plan by turning your body into a fat loss maker. In addition to the advantages of this supplement in fat burning and weight reduction, it likewise supports the function of the body's immune system and is an effective antioxidant. Considering that L-Carnitine supplements are safe and occur naturally it can likewise assist you melt fat and increase energy for most exercises. With a better material of L-carnitine in the body, it will be easier to burn fat and increase the energy material. Considering that L-carcinol assists to carry more fat acids into the cells to burn energy, one would believe that this would also assist to burn fat and slim down. For example, an animal research study published in the Annals of Nutrition and Metabolism (2002) has actually shown that additional L-carnitine in combination with a calorie-reduced diet does not increase body composition or weight-loss. Another animal research study published in The Annal of Nutrition & Metabolisms (2004 ), for example, found that L-carcinine supplementation did not increase fat loss and endurance training achieved this objective. Extra L-carnitine can help to make up for shortages in the amino acids methionine and lysine in people on a plant-based diet plan who do not have sufficient quantities of these amino acids in animal products. As many individuals lack an adequate diet that produces amino acid derivatives in big amounts, they count on L-carcitine dietary supplements (e.g. GNC Isatori (r) L. Carnitine LS3 (tm)) to support their weight-loss efforts. A study published in the Journal of Physiology shows that increasing the amount of carnitine in the muscles helps to avoid fat build-up by increasing fat loss and energy usage during physical activity. L-carnitine At MD Ageless Solutions, we found the most reliable way to resolve weight loss problem with the help of L-carbonitin preparations that are known to help weight loss and deal other health advantages. Weight loss Since L-carnitine helps to burn fat for energy, numerous people presume that more of it will assist them lose weight. It has actually been recommended however that its ability to carry more fat acids into the cells to burn energy makes it an effective performance booster and it is helpful for fat burning and weight loss. The mix of adenosine and L-carnitine can assist you increase your weight loss strategy by turning your body into a fat burning device. Because L-carcinol assists to carry more fat acids into the cells to burn energy, one would believe that this would also assist to burn fat and lose weight.
Green Tea ExtractsDid you know that drinking Green Tea tea, in particular, assist you slim down and get slim? Well, several looks into have discovered evidences that could associate Green Tea tea to weight-loss. A few of these evidences showed that Green Tea teas can help you burn fat and calories. A recent clinical research study particularly supports the capability of the Green Tea green tea to burn fat and boost metabolism. In their conclusion, the scientists who carried out the study mentioned that green tea has thermogenic properties and promotes fat oxidation beyond that explained by its caffeine content. With a variety of proofs that could like Green Tea tea to weight-loss, it's no surprise that today Green Tea slimming tea are becoming highly available in the market. These Green Tea slimming teas are produced normally with the mix of conventional Green Tea herbs, and are meant for those who want to reduce weight and get slim.
Is Java Burn Diet Pills?Some people take supplements to assist the body drop weight without impacting other bodily functions. Switching to regular low-fat products and decreasing your calorie consumption can lead to weight-loss. Seven What You Should Eat Do not forget that it is important for you to work out correctly. In the early morning, when you wake up, drink a glass of green tea or coffee to get the results of the ideal day for weight loss. Part of the reason for this is the enhanced metabolic rate and user experience that assists the body decrease fat and lose that additional inch of waist that is so tough to achieve. The weight loss menu also includes a big percentage of veggies and fruits and a proportion of other proteins and fats. Java Burn has been checked for negative effects and red peppers seem to be a not likely source of weight loss. What I do learn about marathons is that Remigio Jonathan Antoine, who has a weight loss and weight loss diet plan behind him, could not describe in a short book what was going on, which was an unfortunate thing. Java Burn is a weight loss supplement that helps melting fat and enhancing metabolic process. Java Burn is a mix of natural dietary boosters combined as a formula by Mike Banner.
Lose Weight Without Exercise
What if somebody informs you that weight loss is not as difficult as it looks and there are actual items that might assist you? Java Burn weight loss supplement is one of of those products that encourages the body to get better shape, utilizing its natural functions. Read this complete Java Burn evaluation to find out more about its efficacy and advantages.
What is Java Burn?
Java Burn is a simple, revolutionary, and affordable supplement with tested weight reduction benefits. Java Burn is made from 100% natural components, based on the ancient weight-loss treatments from Japan. This formula does not include artificial components, additives, toxic substances, or fillers; More than a diet tablet, Java Burn is a metabolic booster. It comes in a powder kind that makes its usage much more convenient. Based upon the details shared online, it alleviates inflammation that decreases metabolic process and help in fat layering. Once the inflammation is under control, the body returns to a healthy metabolic rate and utilizes the saved fat to create energy and run cell functions. Unlike other powdered supplements, JavaBurn has even saved you from determining the dose. It comes in little prepacked sachets; each packet is one day’s dosage. Just open the bundle, blend it into a glass of water and develop a drink that is your partner in weight-loss. One pack of Java Burn has 30 portions and is enough for one entire month. 2 Billion Probiotic
The Creator Of Java Burn Powder
As discussed in the past, Java Burn is a product of Mike Banner, who is not a medical expert and inadvertently found this formula. He was presented to one organic component that has been utilized for centuries to manage digestion and immunity. After learning about it, he thought about making it commercially available for everyone who is having a hard time with weight problems. Mike took a trip to Japan to meet an associate, Dr. Tamaki, who presented him to this weight loss tonic. He was told about how Japanese individuals have actually constantly preserved their health, and it is unusual to discover any fat and unhealthy person in tribal locations, all due to the fact that of their diet plan. Further questions, research, and info lead to other dietary ingredients that work well for the body and are removed from the modern, junk-based diet. At this time, Mike was sure about creating this ingredient and forming something that is more simple to use than taking in the plants. His struggle led him to the production of Java Burn powder, which turned out to be a big success. It is presently readily available online for direct purchase. 2 Billion Probiotic
Rapid Weigh Loss With Java Burn 2 Billion Probiotic
Age modifications whatever from the outer look, physical health, psychological health, and the capability to function normally. It is possible for metabolic process to change with age and become sluggish, resulting in weight gain and weight problems. When you are aging, this does not mean that you have to live an unhealthy and unsightly life. Java Burn deals with the real concern in weight loss, which is chronic inflammation in the gut. The ingredients utilized in this supplement are anti-inflammatory, immune-modulating, and relaxing; as a result, the body returns to the healthy track within a couple of weeks. This kind of weight reduction is much better than spending money on options that may or might not work. Though private outcomes might vary, weight reduction with Java Burn supplement is legitimate, and the results would appear within a couple of weeks. A few of the preliminary signs consist of cravings control, low yearnings, no state of mind swings, total digestion, high energy levels, and visible body fat loss. As I specified in my Java Burn Review, it contains 100% natural components that work with coffee to stimulate metabolic process and burn the excess pounds that have actually accumulated in the body. According to the makers of Java Burn, caffeine can speed up metabolism and achieve weight loss results if bundled with other active ingredients of Java Burn.Java Burn delivers effective weight loss results in a short time. Java Burn is a daily supplement users can include to their coffee to enhance energy throughout the day and help them burn more weight. Java Burn is a weight loss supplement that assists to melt fat and enhance metabolic process. Java Burn is a weight loss supplement that helps melting fat and enhancing metabolism. 2 Billion ProbioticJava Burn And Cholesterol A green and lush oasis in the middle of a scorching dessert. A cool breeze on a hot summer night. A brilliant light in the end of a cold and dark tunnel. Green tea and cholesterol. For the millions and countless people suffering from high cholesterol green tea might be that light. You can browse and search the Internet for subjects on green tea and cholesterol and would develop numerous hits. Cholesterol, triglycerides, the protein apoB in LDLs, are words dreaded by humans of the modern age. This brand-new century is expected to end up being the century of medical wonders, the green tea, lowly as it might sound looks very promising as several investigates have actually revealed. This might be the decade of green tea and cholesterol. More great news is it's not simply green tea and cholesterol; it's likewise green tea and cancer. Several studies have revealed that the anti-oxidants are present in green tea. The Journal of the National Cancer Institute published the outcomes of an epidemiological research study suggesting that drinking green tea lowered the risk of esophageal cancer in Chinese men and women by almost sixty percent. Another research study done by the University of Purdue researchers just recently concluded that a substance in green tea hinders the development of cancer cells. In another research study by the University of Kansas figured out that EGCG might explain why the rate of heart problem among Japanese men is quite low, even though around seventy-five percent are smokers. And more good news! It's not just green tea and cholesterol; it's likewise green tea and hypertension. Constantly consuming 5 to 10 cups a day of green tea decreases hypertension. For more that 4,000 years the Chinese have actually understood about the medical advantages of green tea given that utilizing it to deal with everything from headaches to depression. It's not simply green tea and cholesterol; it's also green tea and depression! Consuming green also is reported to be practical with rheumatoid arthritis, Cardiovascular illness, infection, and impaired immune function. Green tea is rich in catechin polyphenols, particularly epigallocatechin gallate (EGCG). EGCG is a great anti-cancer component. Polyphenol restricts the unfavorable impacts of smoking cigarettes and a fatty diet plan. It's not simply green tea and cholesterol; it's likewise green tea and weight-loss. The American Journal of Clinical Nutrition released a report that discovered that guys who were offered a combination of caffeine and green tea extract burned more calories than those offered just caffeine. How about green tea and tooth decay anyone? Its bacteria-destroying capabilities eliminate the germs that trigger oral decay. It's not just green tea and cholesterol, it's also green tea and germs. Why is it that it's green tea and cholesterol not oolong tea or black tea? As we all know there are 3 types of tea, green, oolong and black. All of these originated from the leaves of the Camellia sinensis plant. Why green? Green tea leaves are steamed, which prevents the EGCG substance from being oxidized while oolong and black tea leaves are made from dried or fermented leaves, which triggers loss of EGCG. We need to have found out speaking mandarin or fukien a long period of time ago and learnt more about green tea and cholesterol decreasing the Chinese method. There is more to green tea and cholesterol, search the web and get to understand more of the heath advantages you might get from green tea. Does anybody understand how to state green tea in Chinese? More great news is it's not simply green tea and cholesterol; it's also green tea and cancer. It's not simply green tea and cholesterol; it's likewise green tea and high blood pressure. It's not just green tea and cholesterol; it's also green tea and weight loss. It's not just green tea and cholesterol, it's likewise green tea and germs. Reduce Weight With Java Burn Fat active ingredients such as garcinia, cambogia, green tea extract, purple tea extract (THG), higenamine, theobromine and caffeine reduce cravings, slow fat absorption and boost metabolic process to burn more calories than body fat. Java Burn is tasteless, dissolves in your coffee, works with any type of coffee you consume, and has all sorts of side results. As I stated in my Java Burn Review, it consists of 100% natural components that work with coffee to promote metabolic process and burn the excess pounds that have actually built up in the body. Java Burn costs just $50 for a month and recharges your morning cup of coffee by boosting your metabolism and speeding up the results of weight loss. The ingredients of the Java Burn powder supplement are packed with anti-oxidants and other compounds that support weight loss and support your health. According to the makers of Java Burn, caffeine can accelerate metabolism and attain weight loss results if bundled with other components of Java Burn.Java Burn delivers effective weight loss results in a brief time.
How To Use Java BurnJava Burn is an everyday supplement users can add to their coffee to increase energy throughout the day and help them burn more weight. Java Burn uses 100% natural, vegan, Gluten-free and gm-free active ingredients to increase metabolic process and speed up results in weight loss. Java Burn is a weight loss supplement that assists to melt fat and enhance metabolism. For numerous individuals, coffee is the focus for weight loss and sleep, however there has been increasing proof that coffee can have a negative impact on your health, especially if you buy inferior products from third-party markets such as the Java Burn scam. Consuming coffee is great, but how dreadful your metabolism is is is an extremely charged argument between nutritionists, health experts, and everyone else, and no doubt purchasing the wrong Java Burn products brings out the riskiest aspects, with effects that can be severe, dreadful, and undesirable.
2 Billion Probiotic